Diabetes Drugs. So you think these are helping you?

Diabetes is reaching epidemic proportions. One of the main reasons for this is that diabetes is a direct 'side-effect' of many conventional drugs and treatments. Yet, far from having done enough damage, the conventional medical establishment gives us more drugs to treat the disease.

So what are these drugs like? What 'side-effects', or more accurately, what diseases, do diabetes drugs cause?

The dangers of the diabetes Avandia were so serious the drug was eventually banned in the UK and Europe in 2010. I have written about Avandia in previous blogs, and if you want to know the dangers of this drug, click the links here:

Avandia. Still on sale! (July 2010).

Avandia is banned (September 2010).

Avandia. Still on sale! (April 2011).

Another diabetes drug, Actos, has more recently been banned in India, German and France - because it is known to cause bladder cancer, congestive heart failure and death. It is, to the best of my knowledge, still on sale in the rest of the world! Indeed, Actos has been one of the world's most widely prescribed drugs for Type 2 diabetes. But it increases the risk of bladder cancer, the manufacturer knew this, and were fined $9bn by the USA courts for withholding the information!

And it is not just Avandia and Actos. In this blog, "Diabetes Drugs. The cost to our health", in May 2013) I described the harm caused by drugs called Victoza, Byetta, Nesina and Januvia.

The Agora Health website said this about the diabetes drug, Victoza, which was found to cause a rare kind of thyroid cancer, and pancreatitis, and could therefore be deadly.

“Victoza proved to be so dangerous that, in 2012, the FDA received a petition asking that the agency remove it from the market immediately. Even though Victoza "puts patients at higher risk of thyroid cancer, pancreatitis (and) serious allergic reactions", the FDA denied this request... as expected! 

And in July 2013, I wrote this blog, "Diabetes. Are patients better off with, or without these conventional drugs".

So perhaps we might expect that our drug regulators might be expected to be more cautious when approving new Big Pharma drugs! Not a bit of it!

Recently, the American Food and Drug Administration (FDA) approved yet another diabetes drug that is riddled with serious and harmful ‘side effects’ - that is the drug causes disease!

Another Avandia? Another Actos? Probably. And the drug, called Tanzeum, will probably kill as many people as its predecessors before any action will be taken to protect patients. Tanzeum, a drug that has to be injected into the bloodstream, is designed to mimic a hormone that causes the pancreas to release insulin.

Drug Regulators, like the FDA in the USA, and MHRC in the UK, are aware of the dangers, but they take no action. 

Agora Health warned (in April 2014) about another diabetes drug, Invokana, and described it as a drug to be avoided, and outlined the futile efforts to ban it

“In typical FDA fashion, it's allowing GlaxoSmithKline (GSK), the maker of Tanzeum, to conduct a 15-year study for a rare kind of cancer called medullary thyroid carcinoma that could be linked to Tanzeum. You read that right - 15 years! 

So GSK will also report back to the FDA about the heart risks of Tanzeum, but not, of course, until the drug has been causing disease, and killing people, for a very long time!

So are there any diabetes drug not mentioned in this list? There probably are lots more. But would you want to take the chance that these are any safer? It is not the wise option. We all need to learn from experience. Conventional medical drugs do not just cause 'side-effects', they cause disease and death!

Diabetes. Are patients better with, or without these conventional drugs?

Anyone suffering from Diabetes, and in Britain, about 2.5 million people do, must be wondering whether they are better off with, or without the drugs they are prescribed by their NHS doctor. 

A Channel 4 Dispatches programme, broadcast on 10th June 2013 set the scene. It linked certain diabetes drugs (it mentioned Januvia, Victoza and Byetta) with Pancreatitis and Pancreatic cancer. Despite these concerns, the programme said that the Big Pharma drug companies were

     (i) refusing to release data they had gathered on the drugs,
     (ii) but they were interested in using the drugs for the growing problem of Obesity.

This is quite typical of what is happening in the Conventional Medical world. On the one hand, a complete lack of transparency when it comes to responding to concern about serious adverse reactions to drugs. But, on the other hand, a desire to use drugs in other, more lucrative areas of ill-health.

In both cases, the patient appears to be the last to be considered.

As always, when discussing the disease-inducing-effects (DIEs) of pharmaceutical drugs, a question is posed by the conventional medical establishment. Do the benefits of the drugs (in this case, for the treatment of Diabetes) outweigh the risk (in taking drugs that cause Pancreatitis and/or Pancreatic cancer).

One of the drugs concerned, Januvia, has apparently been found to double the risk of developing acute pancreatitis. This was the result of a study, published in the Journal of the American Medical Association (JAMA), in February 2013. The study found that in most cases, hospital admission for pancreatitis happened within the first 60 days of patients taking Januvia.

The makers of Januvia, Merck, have long rejected any link between Januvia and pancreatitis!

The link with pancreatic cancer is even more serious, as it is a disease that kills 80% of people within the first year of diagnosis. There is research, published in 2011, indicating that Januvia could increase the risk of of pancreatic cancer (by 172%) and thyroid cancer too (by 48%).

Equally, what cannot be denied is that Januvia is a money-spinner, one of Mercks best-selling drugs, earning an estimated $4.1 billion in 2012.

So what are the drug regulators doing? Not, it would seem, very much. The FDA announced in March 2013 that 'it will investigate' the risks associated with Januvia. Yet, in the meantime, there is little evidence that any move has been made to inform patients, or that there is much concern about those people who might contract pancreatitis, or pancreatic cancer, during the time it takes to investigate the drug. Not much urgency there, it would seem!

Yet this cannot be considered to be a new linkage. As Agora Health stated in their 'Daily Health eAlert  (June 2013), the FDA were aware of the dangers of Januvia as early as 2006, as between October 2006 and February 2009, the FDA received reports of 88 cases that linked this drug with pancreatitis.

It would seem that being diabetic, not an easy one at the best of times, is being made far worse by the drugs the Conventional Medical Establishment gets them to take.

Victoza, another diabetes drug, was introduce in 2012. Even at the testing stage, animal studies indicated that it cause thyroid tumours, and human studies indicated that it caused pancreatitis. So why was it approved? Only the drug regulators know. But despite the evidence, the drug was uncompromisingly heralded as a 'breakthrough' in the treatment of type-2 diabetes! Other drugs, of the same type, are called Byetta, Exenatide, Liraglutide - and of course, Januvia.

Dispatches reported that the British Medical Journal (BMJ) had looked at all the evidence concerning this drugs, and had concluded that the manufacturers (including Merck, Novo Nordisk and Amylin Pharmaceuticals) may have been trying to hide the potential harmful reactions the caused. Dr. Deborah Cohen, from BMJ, is reported saying that whilst the evidence of the trial "may seem inconclusive",

          "When considered alongside other emerging and long-standing evidence, a worrying picture emerges, posing serious questions about the safety of this class of drug".

So, are diabetes patients better off with these drugs, or without them?

Remember the diabetes drug, Avandia? Some people dubbed it as 'the killer drug' - although it must be said that Avandia has many rivals to this claim! Recall that it was banned throughout Europe in September 2010, as it was found to significantly increase the risk of heart attacks? Yet Avandia was marketed from 2000, and for 10 years it was allowed to cause heart attacks and strokes - whilst it was being 'investigated' by the drug regulators.

Will it take as long for these 'new' drugs to be banned? Will the drug regulators allow pharmaceutical companies to profit from drugs that are causing death whilst they 'investigate' the problems? How long will it take before the needs of patients come before the profits of drug companies?

One thing that every diabetes sufferer can do is to challenge their doctor, challenge the NHS, challenge the Department of Health, challenge their MP - and demand safer medicine. We all need to ask the question. Is the need to treat diabetes worth risk of getting acute pancreatitis, and pancreatic cancer? Do the benefits of these drugs really outweigh the risks?

Diabetes Drugs. The cost to our health

Diabetes drugs cost us dearly!

One drug, now banned, is Avandia. Not long ago, GlaxoSmithKline (GSK), were fined $3 billion when they pleaded guilty to a felony in the USA. Apparently, when they marketed the drug GSK admitted that they decided to hide data about Avandia increasing the risk of heart attacks, and congestive heart failure. They continued to do so between 2001 to 2007, during which time they made enormous profits - at the expense of our health.

So was this just a one-off situation? A rogue Big Pharma company who broke the rules? No, GSK's biggest rival, Takeda Pharmaceutical Co, which makes a diabetes drug called Actos, have now been accused of withholding safety data in order to make it appear safer than its rival, Avandia. It is know that the adverse reactions to Actos include diseases such as bladder cancer and congestive heart failure.

So, was this just a two-off situation? No. Other Big Pharma companies have since sought to fill the gap left by Avandia and Actos, and introduced more diabetes drugs. Four years ago, Victoza was introduced, the latest magic pill,the cure for diabetes. Unfortunately, it has since been discovered that this drug can cause disastrous harm to the pancreas, increasing the risk of an early, unnecessary death.

So was this just a three-off situation? No. According to Agora Health's 'Daily Health Alert', a new study in the journal Diabetes has now implicated more than a dozen drugs, in the same class as Victoza. Brand names include Byetta, Nesina, and Januvia, and that US researchers have found that these drugs, incretin mime tics, can drastically increase your risk of pancreatitis.

          "Here's where it gets insane. None of this is new to the medical authorities. In fact, the American Food and Drug Administration (FDA) previously warned that post-marketing reports about these drugs include "fatal and serious nonfatal cases" of acute pancreatitis". 

There is also evidence that Januvia can increase a patient's risk of cancer.

In their newsletter, dated 3rd July 2012, and their magazine, dated November 2012, "What Doctor's Don't Tell You" stated that the 'new generation' of diabetes drugs were 'killers'. They said that research, at the Cleveland Clinic in Ohio, had found that anyone taking these drugs were 50% more likely to die than people taking the older diabetes drugs. The drugs Glucotrol, Daonil, and Diabeta were analysed in this research.

So this is yet another situation that demonstrates that the Drug Regulation system, designed as they are to protect patients, quite simply fail to do so. At the test stage evidence of drug dangers are either hidden, or not acted upon even when they are known. Once introduced, drugs are allowed to harm patients, and Big Pharma companies are allowed to profit from them, with only inadequate restrictions being placed on their prescription. In the meantime, our doctors are offered inducements, by the drug companies to sell the drugs; and in the main, they meekly go along with it.

Only when pharmaceutical drugs are found to be killers, and only when the evidence is overwhelming and incontrovertible, do drug regulators act to protect patients.

See 'Medical Science: the failure to protect' for more about this.

There has been an epidemic of diabetes in recent decades, at least partly caused by other pharmaceutical drugs, such as diuretics and Beta Blockers, and the result is that many diabetics are, or have been, taking these 'anti-diabetes' drugs. Clearly, these patients cannot be assured that they are safe taking them. There is a long history of too much obfuscation, too many lies, a record of fraud and dishonesty, a lack of concern about patient safety,within the entire conventional medical establishment (starting with Big Pharma companies, through regulation, right up to our doctors).

So what should patients do? The Daily Health Alert says that anyone taking any diabetes drugs should talk to their doctors "about an alternative treatment plan". They add that 

          "... you can usually restore normal pancreas function by making the right dietary changes. These might not be easy but they certainly won't increase your risk of cancer, heart attack or premature death".

If this is so, it has to asked - why is it that doctors don't prescribe a better diet, and not dangerous pharmaceutical drugs?